CC14B Polyclonal Antibody

产品详情

产品名称

CC14B Polyclonal Antibody

产品货号

YM-A08128

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

54kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from part region of human protein AA range: 407-457

特异性

CC14B Polyclonal Antibody detects endogenous levels of protein.

基因名称

CDC14B

蛋白名称

Dual specificity protein phosphatase CDC14B (CDC14 cell division cycle 14 homolog B)

别名

基因ID-1

8555

SwissProt

O60729

背景

cell division cycle 14B(CDC14B) Homo sapiens The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus, nucleolus. Nucleus, nucleoplasm. Following DNA damage, translocates from the nucleolus to the nucleoplasm and interacts with FZR1/CDH1.