OSCAR Polyclonal Antibody

产品详情

产品名称

OSCAR Polyclonal Antibody

产品货号

YM-A08486

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

31kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from part region of human protein

特异性

OSCAR Polyclonal Antibody detects endogenous levels of protein.

基因名称

OSCAR

蛋白名称

Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3)

别名

基因ID-1

126014

SwissProt

Q8IYS5

背景

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],

细胞定位

[Isoform 1]: Secreted .; [Isoform 2]: Cell membrane ; Single-pass type I membrane protein .