STAB2 Polyclonal Antibody

产品详情

产品名称

STAB2 Polyclonal Antibody

产品货号

YM-A08569

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

IHC,IF

分子量

280kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-300;IF 1:100-300;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 980-1060

特异性

STAB2 Polyclonal Antibody detects endogenous levels of protein.

基因名称

STAB2 FEEL2 FELL FEX2 HARE

蛋白名称

Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)]

别名

基因ID-1

55576

SwissProt

Q8WWQ8

背景

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Only a small amount appears to be present at the cell surface (PubMed:17145755).