PPM1B Polyclonal Antibody

产品详情

产品名称

PPM1B Polyclonal Antibody

产品货号

YM-A08598

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,ELISA

分子量

52kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 310-390

特异性

PPM1B Polyclonal Antibody detects endogenous levels of protein.

基因名称

PPM1B PP2CB

蛋白名称

Protein phosphatase 1B (Protein phosphatase 2C isoform beta) (PP2C-beta)

别名

基因ID-1

5495

SwissProt

O75688

背景

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytosol . Membrane ; Lipid-anchor . Weakly associates at the membrane and N-myristoylation mediates the membrane localization. .