CSPG4 Polyclonal Antibody

产品详情

产品名称

CSPG4 Polyclonal Antibody

产品货号

YM-A08621

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

IHC,IF

分子量

255kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-300;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 1910-1990

特异性

CSPG4 Polyclonal Antibody detects endogenous levels of protein.

基因名称

CSPG4 MCSP

蛋白名称

Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan)

别名

基因ID-1

1464

SwissProt

Q6UVK1

背景

A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Apical cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein ; Extracellular side . Cell surface . Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. Localizes to the plasma membrane of oligodendrocytes (By similarity). .