TPP1 Polyclonal Antibody

产品详情

产品名称

TPP1 Polyclonal Antibody

产品货号

YM-A08647

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,ELISA

分子量

61kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 10-90

特异性

TPP1 Polyclonal Antibody detects endogenous levels of protein.

基因名称

TPP1 CLN2 GIG1 UNQ267/PRO304

蛋白名称

Tripeptidyl-peptidase 1 (TPP-1) (Cell growth-inhibiting gene 1 protein) (Lysosomal pepstatin-insensitive protease) (LPIC) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I)

别名

基因ID-1

1200

SwissProt

O14773

背景

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008],

细胞定位

Lysosome . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .