DSC2 Polyclonal Antibody

产品详情

产品名称

DSC2 Polyclonal Antibody

产品货号

YM-A08669

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

99kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 150-230

特异性

DSC2 Polyclonal Antibody detects endogenous levels of protein.

基因名称

DSC2 CDHF2 DSC3

蛋白名称

Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)

别名

基因ID-1

1824

SwissProt

Q02487

背景

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome .