HECAM Polyclonal Antibody

产品详情

产品名称

HECAM Polyclonal Antibody

产品货号

YM-A08689

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

45kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 10-90

特异性

HECAM Polyclonal Antibody detects endogenous levels of protein.

基因名称

HEPACAM

蛋白名称

Hepatocyte cell adhesion molecule (Protein hepaCAM)

别名

基因ID-1

220296

SwissProt

Q14CZ8

背景

The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011],

细胞定位

Cytoplasm . Membrane; Single-pass type I membrane protein; Cytoplasmic side . In MCF-7 breast carcinoma and hepatic Hep 3B2.1-7 and Hep-G2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1.