BACE2 Polyclonal Antibody

产品详情

产品名称

BACE2 Polyclonal Antibody

产品货号

YM-A08714

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,ELISA

分子量

56kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 210-290

特异性

BACE2 Polyclonal Antibody detects endogenous levels of protein.

基因名称

BACE2 AEPLC ALP56 ASP21 CDA13 UNQ418/PRO852

蛋白名称

Beta-secretase 2 (Aspartic-like protease 56 kDa) (Aspartyl protease 1) (ASP1) (Asp 1) (Beta-site amyloid precursor protein cleaving enzyme 2) (Beta-site APP cleaving enzyme 2) (Down region aspartic protease) (DRAP) (Memapsin-1) (Membrane-associated aspartic protease 1) (Theta-secretase)

别名

基因ID-1

25825

SwissProt

Q9Y5Z0

背景

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Golgi apparatus . Endoplasmic reticulum. Endosome.