DHX58 Polyclonal Antibody

产品详情

产品名称

DHX58 Polyclonal Antibody

产品货号

YM-A08797

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

74kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human protein . at AA range: 451-500

特异性

DHX58 Polyclonal Antibody detects endogenous levels of protein.

基因名称

DHX58 D11LGP2E LGP2

蛋白名称

Probable ATP-dependent RNA helicase DHX58 (Probable ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)

别名

基因ID-1

79132

SwissProt

Q96C10

背景

function:Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,similarity:Belongs to the helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with DDX58 and probably blocks its homomultimerization.,

细胞定位

Cytoplasm .