URP2 Polyclonal Antibody

产品详情

产品名称

URP2 Polyclonal Antibody

产品货号

YM-A09121

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

73kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000;ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from part region of human protein AA range: 52-102

特异性

URP2 Polyclonal Antibody detects endogenous levels of protein.

基因名称

FERMT3 KIND3 MIG2B URP2

蛋白名称

Fermitin family homolog 3 (Kindlin-3) (MIG2-like protein) (Unc-112-related protein 2)

别名

基因ID-1

83706

SwissProt

Q86UX7

背景

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010],

细胞定位

Cell projection, podosome . Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. .