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产品详情
产品名称
PLIN3 Polyclonal Antibody
产品货号
YM-A09322
规格
50μL;100μL
种属反应
Human,Mouse
实验应用
WB,ELISA
分子量
47kD
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from part region of human protein
特异性
PLIN3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PLIN3 M6PRBP1 TIP47
蛋白名称
Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17)
别名
基因ID-1
10226
SwissProt
O60664
背景
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009],
细胞定位
Lipid droplet . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Membrane associated on endosomes (PubMed:15545278). Detected in the envelope and the core of lipid bodies and in lipid sails (PubMed:15545278). .
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