K2C6B rabbit pAb

产品详情

产品名称

K2C6B rabbit pAb

产品货号

YM-A09442

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human K2C6B AA range: 93-143

特异性

This antibody detects endogenous levels of K2C6B at Human/Mouse

基因名称

KRT6B K6B KRTL1

蛋白名称

K2C6B

别名

Keratin, type II cytoskeletal 6B;Cytokeratin-6B;CK-6B;Keratin-6B;K6B;Type-II keratin Kb10;

基因ID-1

3854

SwissProt

P04259

背景

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

细胞定位

keratin filament,extracellular exosome,