SNX13 rabbit pAb

产品详情

产品名称

SNX13 rabbit pAb

产品货号

YM-A09599

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB

分子量

105kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human SNX13 AA range: 602-652

特异性

This antibody detects endogenous levels of SNX13 at Human/Mouse

基因名称

SNX13 KIAA0713

蛋白名称

SNX13

别名

Sorting nexin-13;RGS domain- and PHOX domain-containing protein;RGS-PX1;

基因ID-1

23161

SwissProt

Q9Y5W8

背景

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],

细胞定位

Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .