SIAH1 rabbit pAb

产品详情

产品名称

SIAH1 rabbit pAb

产品货号

YM-A10488

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human SIAH1 AA range: 157-207

特异性

This antibody detects endogenous levels of SIAH1 at Human/Rat

基因名称

SIAH1 HUMSIAH

蛋白名称

SIAH1

别名

基因ID-1

6477

SwissProt

Q8IUQ4

背景

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.