MEFV rabbit pAb

产品详情

产品名称

MEFV rabbit pAb

产品货号

YM-A11663

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human MEFV AA range: 517-567

特异性

This antibody detects endogenous levels of human MEFV

基因名称

MEFV MEF

蛋白名称

Pyrin (Marenostrin)

别名

基因ID-1

4210

SwissProt

O15553

背景

细胞定位

[Isoform 1]: Cytoplasm, cytoskeleton . Cell projection, ruffle . Cell projection, lamellipodium . Nucleus . Cytoplasm . Cytoplasmic vesicle, autophagosome . Associated with microtubules and with the filamentous actin of perinuclear filaments and peripheral lamellar ruffles (PubMed:11468188). In pre-apoptotic cells, colocalizes with PYCARD/ASC in large specks (inflammasomes) (PubMed:11468188). In migrating monocytes, strongly polarized at the leading edge of the cell where it colocalizes with polymerizing actin and PYCARD/ASC (PubMed:11468188). .; [Isoform 2]: Nucleus .