α-tubulin Polyclonal Antibody

产品详情

产品名称

α-tubulin Polyclonal Antibody

产品货号

YM-A11708

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB

分子量

52kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:2000

组成

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

克降性

Polyclonal

克隆号

免疫原

Recombinant Protein of Tubulin alpha-1A chain

特异性

The antibody detects endogenous α-tubulin protein.

基因名称

TUBA1A

蛋白名称

Tubulin alpha-1A chain

别名

YM3217

基因ID-1

7846;10376

SwissProt

Q71U36;P68363

背景

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

细胞定位

Cytoplasm, cytoskeleton.