WIPI2 Rabbit Polyclonal Antibody

产品详情

产品名称

WIPI2 Rabbit Polyclonal Antibody

产品货号

YM-A11710

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF

分子量

49kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-300;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Recombinant Protein of WIPI2

特异性

The antibody detects endogenous WIPI2 protein

基因名称

WIPI2 CGI-50

蛋白名称

WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)

别名

WD repeat domain phosphoinositide-interacting protein 2;WIPI-2;WIPI49-like protein 2;

基因ID-1

26100

SwissProt

Q9Y4P8

背景

WD repeat domain, phosphoinositide interacting 2(WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008],

细胞定位

Preautophagosomal structure membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to omegasomes membranes which are endoplasmic reticulum connected structures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P. .