Kv11.1 Polyclonal Antibody

产品详情

产品名称

Kv11.1 Polyclonal Antibody

产品货号

YM-A11750

规格

50μL;100μL

种属反应

Rat,Mouse

实验应用

WB,IHC,IF

分子量

62kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic Peptide of Kv11.1

特异性

Kv11.1 protein(A262) detects endogenous levels of Kv11.1

基因名称

KCNV2

蛋白名称

Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2)

别名

KCNV2;Potassium voltage-gated channel subfamily V member 2;Voltage-gated potassium channel subunit Kv8.2

基因ID-1

169522

SwissProt

Q8TDN2

背景

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008],

细胞定位

Cell membrane; Multi-pass membrane protein. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.