KCNN2 (SK2) Polyclonal Antibody

产品详情

产品名称

KCNN2 (SK2) Polyclonal Antibody

产品货号

YM-A11757

规格

50μL;100μL

种属反应

Human,Rat,Mouse

实验应用

WB,IHC,IF

分子量

70,26kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:1000-2000;IHC 1:100-200;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthetic Peptide of KCNN2 (SK2)

特异性

KCNN2(SK2) protein(A244) detects endogenous levels of KCNN2(SK2)

基因名称

蛋白名称

别名

YM3565

基因ID-1

3781

SwissProt

Q6PJI0

背景

potassium calcium-activated channel subfamily N member 2(KCNN2) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013],

细胞定位

smooth endoplasmic reticulum,plasma membrane,cell surface,integral component of membrane,Z disc,T-tubule,neuronal cell body,dendritic spine,