ATG7 Rabbit Polyclonal Antibody

产品详情

产品名称

ATG7 Rabbit Polyclonal Antibody

产品货号

YM-A11828

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF

分子量

78kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC 1:50-300;WB 1:500-2000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Recombinant Protein of ATG7

特异性

The antibody detects endogenous ATG7 protein

基因名称

ATG7 APG7L

蛋白名称

Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)

别名

Ubiquitin-like modifier-activating enzyme ATG7;ATG12-activating enzyme E1 ATG7;Autophagy-related protein 7;APG7-like;hAGP7;Ubiquitin-activating enzyme E1-like protein;

基因ID-1

10533

SwissProt

O95352

背景

This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

细胞定位

Cytoplasm . Preautophagosomal structure . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. .