STIP1/HOP Rabbit pAb

产品详情

产品名称

STIP1/HOP Rabbit pAb

产品货号

YM-A11864

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,WB

分子量

64kD

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

IHC1:50-200;WB 1:1000-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human STIP1/HOP AA range: 250-300

特异性

This antibody detects endogenous levels of STIP1/HOP at Human, Mouse,Rat

基因名称

STIP1

蛋白名称

STIP1/HOP

别名

Stress-induced-phosphoprotein 1;STI1;Hsc70/Hsp90-organizing protein;Hop;Renal carcinoma antigen NY-REN-11;Transformation-sensitive protein IEF SSP 3521;

基因ID-1

10963

SwissProt

P31948

背景

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],

细胞定位

Cytoplasm . Nucleus . Dynein axonemal particle .