Myopodin rabbit pAb

产品详情

产品名称

Myopodin rabbit pAb

产品货号

YM-A13036

规格

50μL;100μL

种属反应

Human

实验应用

WB

分子量

宿主

Rabbit

同种型

IgG

修饰

Unmodified

推荐稀释比

WB 1:500-2000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human Myopodin

特异性

This antibody detects endogenous levels of Myopodin at Human

基因名称

SYNPO2

蛋白名称

Synaptopodin-2 (Genethonin-2) (Myopodin)

别名

基因ID-1

171024

SwissProt

Q9UMS6

背景

细胞定位

Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell junction, focal adhesion . Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. In undifferentiated myoblasts strongly expressed in the nucleus, after induction of myotube differentiation is located to both nucleus and cytoplasm along acting filaments, and in differentiated myotubes is located at the Z lines. Upon stress redistributes from cytoplasm of myoblasts and myotubes to the nucleus. Nuclear import is KPNA2-dependent and promoted by phosphorylation by PKA and/or CaMK2, and inhibition of calcineurin. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern, partly overlapping with filamentous actin (PubMed:18371299). .; [Isoform 1]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .; [Isoform 2]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 3]: Cytoplasm, cytoskeleton . Localizes to induced irregular actin bundles with contiguous and punctuated staining. .; [Isoform 4]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with punctuate staining. .; [Isoform 5]: Cytoplasm, cytoskeleton . Localizes to induced actin bundles with contiguous staining. .