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产品详情
产品名称
NELF rabbit pAb
产品货号
YM-A14645
规格
50μL;100μL
种属反应
Human,Mouse,Rat
实验应用
WB
分子量
宿主
Rabbit
同种型
IgG
修饰
Unmodified
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克降性
Polyclonal
克隆号
免疫原
Synthesized peptide derived from human NELF
特异性
This antibody detects endogenous levels of NELF at Human, Mouse,Rat
基因名称
NELF
蛋白名称
Nasal embryonic luteinizing hormone-releasing hormone factor (Nasal embryonic LHRH factor)
别名
基因ID-1
26012
SwissProt
Q6X4W1
背景
细胞定位
Nucleus . Nucleus envelope . Nucleus membrane . Nucleus matrix . Cytoplasm . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein . Cell projection, dendrite . Cell junction, synapse . Cell junction, synapse, synaptosome . Cell junction, synapse, postsynaptic density . Membrane . Found on the outside of the luteinizing-hormone-releasing hormone (LHRH) cell membrane and axons projecting from the olfactory pit and epithelium. Associates with transcriptionally active chromatin regions. Detected at the nuclear membranes of CA1 neurons. Cortical cytoskeleton. Localized in proximal apical dendrites. Colocalizes with CABP1 in dendrites and dendritic spines. Myristoylation is a prerequisite for extranuclear localization. Translocates from dendrites to the nucleus during NMDA receptor-dependent long-term potentiation (LTP) induction of synaptic transmission at Schaffer collateral/CA1 synapses of hippocampal primary neurons and in a importin-dependent manner (By similarity). .
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