Bcl-2 (phospho Ser70) Polyclonal Antibody

产品详情

产品名称

Bcl-2 (phospho Ser70) Polyclonal Antibody

产品货号

YM-A14981

规格

50μL;100μL

种属反应

Human,Monkey

实验应用

WB,IHC,IF,IP,ELISA

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human BCL-2 around the phosphorylation site of Ser70. AA range:41-90

特异性

Phospho-Bcl-2 (S70) Polyclonal Antibody detects endogenous levels of Bcl-2 protein only when phosphorylated at S70.

基因名称

BCL2

蛋白名称

Apoptosis regulator Bcl-2

别名

BCL2;Apoptosis regulator Bcl-2

基因ID-1

596

SwissProt

P10415

背景

BCL2, apoptosis regulator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

细胞定位

Mitochondrion outer membrane ; Single-pass membrane protein . Nucleus membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Cytoplasm .