GSK3α (phospho Ser21) Polyclonal Antibody

产品详情

产品名称

GSK3α (phospho Ser21) Polyclonal Antibody

产品货号

YM-A15071

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,IP,ELISA

分子量

55kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Ser21. AA range:10-59

特异性

Phospho-GSK3α (S21) Polyclonal Antibody detects endogenous levels of GSK3α protein only when phosphorylated at S21.

基因名称

GSK3A

蛋白名称

Glycogen synthase kinase-3 alpha

别名

GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A

基因ID-1

2931

SwissProt

P49840

背景

glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],

细胞定位

apical dendrite;axon;beta-catenin destruction complex;cytoplasm;cytosol;mitochondrion;neuronal cell body;nucleus;postsynapse;proximal dendrite;