HSP27 (phospho Ser15) Polyclonal Antibody

产品详情

产品名称

HSP27 (phospho Ser15) Polyclonal Antibody

产品货号

YM-A15083

规格

50μL;100μL

种属反应

Human,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

26kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human HSP27 around the phosphorylation site of Ser15. AA range:5-54

特异性

Phospho-HSP27 (S15) Polyclonal Antibody detects endogenous levels of HSP27 protein only when phosphorylated at S15.

基因名称

HSPB1

蛋白名称

Heat shock protein beta-1

别名

HSPB1;HSP27;HSP28;Heat shock protein beta-1;HspB1;28 kDa heat shock protein;Estrogen-regulated 24 kDa protein;Heat shock 27 kDa protein;HSP 27;Stress-responsive protein 27;SRP27

基因ID-1

3315

SwissProt

P04792

背景

The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008],

细胞定位

Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. .