p73 (phospho Tyr99) Polyclonal Antibody

产品详情

产品名称

p73 (phospho Tyr99) Polyclonal Antibody

产品货号

YM-A15167

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

73kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human p73 around the phosphorylation site of Tyr99. AA range:66-115

特异性

Phospho-p73 (Y99) Polyclonal Antibody detects endogenous levels of p73 protein only when phosphorylated at Y99.

基因名称

TP73

蛋白名称

Tumor protein p73

别名

TP73;P73;Tumor protein p73;p53-like transcription factor;p53-related protein

基因ID-1

7161

SwissProt

O15350

背景

tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],

细胞定位

Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.