Stat4 (phospho Tyr693) Polyclonal Antibody

产品详情

产品名称

Stat4 (phospho Tyr693) Polyclonal Antibody

产品货号

YM-A15201

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Monkey

实验应用

WB,IHC,IF,IP,ELISA

分子量

86kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human STAT4 around the phosphorylation site of Tyr693. AA range:660-709

特异性

Phospho-Stat4 (Y693) Polyclonal Antibody detects endogenous levels of Stat4 protein only when phosphorylated at Y693.

基因名称

STAT4

蛋白名称

Signal transducer and activator of transcription 4

别名

STAT4;Signal transducer and activator of transcription 4

基因ID-1

6775

SwissProt

Q14765

背景

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

细胞定位

Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.