IκB-β (phospho Thr19) Polyclonal Antibody

产品详情

产品名称

IκB-β (phospho Thr19) Polyclonal Antibody

产品货号

YM-A15249

规格

50μL;100μL

种属反应

Human,Rat,Mouse,

实验应用

WB,IHC,IF,ELISA

分子量

37kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human IkappaB-beta around the phosphorylation site of Thr19. AA range:4-53

特异性

Phospho-IκB-β (T19) Polyclonal Antibody detects endogenous levels of IκB-β protein only when phosphorylated at T19.

基因名称

NFKBIB

蛋白名称

NF-kappa-B inhibitor beta

别名

NFKBIB;IKBB;TRIP9;NF-kappa-B inhibitor beta;NF-kappa-BIB;I-kappa-B-beta;IkB-B;IkB-beta;IkappaBbeta;Thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP-9

基因ID-1

4793

SwissProt

Q15653

背景

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],

细胞定位

Cytoplasm . Nucleus .