CD32 (phospho Tyr292) Polyclonal Antibody

产品详情

产品名称

CD32 (phospho Tyr292) Polyclonal Antibody

产品货号

YM-A15274

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

32kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CD32 around the phosphorylation site of Tyr292. AA range:258-307

特异性

Phospho-CD32 (Y292) Polyclonal Antibody detects endogenous levels of CD32 protein only when phosphorylated at Y292.

基因名称

FCGR2B

蛋白名称

Low affinity immunoglobulin gamma Fc region receptor II-b

别名

FCGR2B;CD32;FCG2;IGFR2;Low affinity immunoglobulin gamma Fc region receptor II-b;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD antigen CD32

基因ID-1

2213

SwissProt

P31994

背景

The Fc fragment of IgG receptor IIb encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

细胞定位

Cell membrane; Single-pass type I membrane protein.