Ron (phospho Ser1394) Polyclonal Antibody

产品详情

产品名称

Ron (phospho Ser1394) Polyclonal Antibody

产品货号

YM-A15295

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC

分子量

152kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CD136/RON around the phosphorylation site of Ser1394. AA range:1351-1400

特异性

Phospho-Ron (S1394) Polyclonal Antibody detects endogenous levels of Ron protein only when phosphorylated at S1394.

基因名称

MST1R

蛋白名称

Macrophage-stimulating protein receptor

别名

MST1R;PTK8;RON;Macrophage-stimulating protein receptor;MSP receptor;CDw136;Protein-tyrosine kinase 8;p185-Ron;CD antigen CD136

基因ID-1

4486

SwissProt

Q04912

背景

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016],

细胞定位

Membrane; Single-pass type I membrane protein.