TIS11B (phospho Ser92) Polyclonal Antibody

产品详情

产品名称

TIS11B (phospho Ser92) Polyclonal Antibody

产品货号

YM-A15338

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA,IHC

分子量

36kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TISB around the phosphorylation site of Ser92. AA range:58-107

特异性

Phospho-TIS11B (S92) Polyclonal Antibody detects endogenous levels of TIS11B protein only when phosphorylated at S92.

基因名称

ZFP36L1

蛋白名称

Zinc finger protein 36 C3H1 type-like 1

别名

ZFP36L1;BERG36;BRF1;ERF1;RNF162B;TIS11B;Zinc finger protein 36;C3H1 type-like 1;Butyrate response factor 1;EGF-response factor 1;ERF-1;Protein TIS11B

基因ID-1

677

SwissProt

Q07352

背景

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

细胞定位

Nucleus . Cytoplasm . Cytoplasmic granule . Cytoplasm, P-body . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner (By similarity). Component of cytoplasmic stress granules (PubMed:15967811). Localizes in processing bodies (PBs) (PubMed:17369404). .