MEK-7 (phospho Thr275) Polyclonal Antibody

产品详情

产品名称

MEK-7 (phospho Thr275) Polyclonal Antibody

产品货号

YM-A15375

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

43kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human MAP2K7 around the phosphorylation site of Thr275. AA range:241-290

特异性

Phospho-MEK-7 (T275) Polyclonal Antibody detects endogenous levels of MEK-7 protein only when phosphorylated at T275.

基因名称

MAP2K7

蛋白名称

Dual specificity mitogen-activated protein kinase kinase 7

别名

MAP2K7;JNKK2;MEK7;MKK7;PRKMK7;SKK4;Dual specificity mitogen-activated protein kinase kinase 7;MAP kinase kinase 7;MAPKK 7;JNK-activating kinase 2;MAPK/ERK kinase 7;MEK 7;Stress-activated protein kinase kinase 4;SAPK kinase 4;S

基因ID-1

5609

SwissProt

O14733

背景

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

细胞定位

Nucleus. Cytoplasm .