Rsk-1/2/3/4 (phospho Ser221/227/S218/232) Polyclonal Antibody

产品详情

产品名称

Rsk-1/2/3/4 (phospho Ser221/227/S218/232) Polyclonal Antibody

产品货号

YM-A15385

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,ELISA

分子量

85kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human RSK1/2/3/4 around the phosphorylation site of Ser221/227/S218/232. AA range:191-240

特异性

Phospho-Rsk-1/2/3/4 (S221/227/S218/232) Polyclonal Antibody detects endogenous levels of Rsk-1/2/3/4 protein only when phosphorylated at S221/227/S218/232.

基因名称

RPS6KA1

蛋白名称

Ribosomal protein S6 kinase alpha-1

别名

RPS6KA1;MAPKAPK1A;RSK1;Ribosomal protein S6 kinase alpha-1;S6K-alpha-1;90 kDa ribosomal protein S6 kinase 1;p90-RSK 1;p90RSK1;p90S6K;MAP kinase-activated protein kinase 1a;MAPK-activated protein kinase 1a;MAPKAP kinase 1a;MAPKAP

基因ID-1

6195;6197;6196;27330

SwissProt

Q15418;P51812;Q15349;Q9UK32

背景

ribosomal protein S6 kinase A1(RPS6KA1) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

细胞定位

Nucleus. Cytoplasm.