PDGFR-α (phospho Tyr849) Polyclonal Antibody

产品详情

产品名称

PDGFR-α (phospho Tyr849) Polyclonal Antibody

产品货号

YM-A15390

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

140kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PDGFRa around the phosphorylation site of Tyr849. AA range:816-865

特异性

Phospho-PDGFR-α (Y849) Polyclonal Antibody detects endogenous levels of PDGFR-α protein only when phosphorylated at Y849.

基因名称

PDGFRA

蛋白名称

Platelet-derived growth factor receptor alpha

别名

PDGFRA;PDGFR2;RHEPDGFRA;Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 antigen-like family member A;CD14

基因ID-1

5156

SwissProt

P16234

背景

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus .