Synaptotagmin 1/2 (phospho Thr202/199) Polyclonal Antibody

产品详情

产品名称

Synaptotagmin 1/2 (phospho Thr202/199) Polyclonal Antibody

产品货号

YM-A15535

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

60kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Thr202. AA range:176-225

特异性

Phospho-Synaptotagmin 1/2 (T202/199) Polyclonal Antibody detects endogenous levels of Synaptotagmin 1/2 protein only when phosphorylated at T202/199.

基因名称

SYT1/SYT2

蛋白名称

Synaptotagmin-1/2

别名

SYT1;SVP65;SYT;Synaptotagmin-1;Synaptotagmin I;SytI;p65;SYT2;Synaptotagmin-2;Synaptotagmin II;SytII

基因ID-1

6857;127833

SwissProt

P21579;Q8N9I0

背景

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010],

细胞定位

Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .