eEF2K (phospho Ser366) Polyclonal Antibody

产品详情

产品名称

eEF2K (phospho Ser366) Polyclonal Antibody

产品货号

YM-A15547

规格

50μL;100μL

种属反应

Human,Rat

实验应用

WB,IHC,IF,ELISA

分子量

105kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366. AA range:331-380

特异性

Phospho-eEF2K (S366) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S366.

基因名称

EEF2K

蛋白名称

Eukaryotic elongation factor 2 kinase

别名

EEF2K;Eukaryotic elongation factor 2 kinase;eEF-2 kinase;eEF-2K;Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase

基因ID-1

29904

SwissProt

O00418

背景

This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],

细胞定位

cytoplasm,cytosol,postsynaptic density,