Syk (phospho Tyr525) Polyclonal Antibody

产品详情

产品名称

Syk (phospho Tyr525) Polyclonal Antibody

产品货号

YM-A15563

规格

50μL;100μL

种属反应

Human,Mouse,Rat,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

72kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr525. AA range:491-540

特异性

Phospho-Syk (Y525) Polyclonal Antibody detects endogenous levels of Syk protein only when phosphorylated at Y525.

基因名称

SYK

蛋白名称

Tyrosine-protein kinase SYK

别名

SYK;Tyrosine-protein kinase SYK;Spleen tyrosine kinase;p72-Syk

基因ID-1

6850

SwissProt

P43405

背景

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

细胞定位

Cell membrane . Cytoplasm, cytosol .