Bmx (phospho Tyr566) Polyclonal Antibody

产品详情

产品名称

Bmx (phospho Tyr566) Polyclonal Antibody

产品货号

YM-A15665

规格

50μL;100μL

种属反应

Human,Mouse

实验应用

WB,IHC,IF,ELISA

分子量

78kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human ETK around the phosphorylation site of Tyr566. AA range:532-581

特异性

Phospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.

基因名称

BMX

蛋白名称

Cytoplasmic tyrosine-protein kinase BMX

别名

BMX;Cytoplasmic tyrosine-protein kinase BMX;Bone marrow tyrosine kinase gene in chromosome X protein;Epithelial and endothelial tyrosine kinase;ETK;NTK38

基因ID-1

660

SwissProt

P51813

背景

This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],

细胞定位

Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.