PKD1 (phospho Tyr463) Polyclonal Antibody

产品详情

产品名称

PKD1 (phospho Tyr463) Polyclonal Antibody

产品货号

YM-A15669

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

130kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Tyr463. AA range:429-478

特异性

Phospho-PKD1 (Y463) Polyclonal Antibody detects endogenous levels of PKD1 protein only when phosphorylated at Y463.

基因名称

PRKD1

蛋白名称

Serine/threonine-protein kinase D1

别名

PRKD1;PKD;PKD1;PRKCM;Serine/threonine-protein kinase D1;Protein kinase C mu type;Protein kinase D;nPKC-D1;nPKC-mu

基因ID-1

5587

SwissProt

Q15139

背景

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010],

细胞定位

Cytoplasm . Cell membrane . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation.