Cdc25B (phospho Ser353) Polyclonal Antibody

产品详情

产品名称

Cdc25B (phospho Ser353) Polyclonal Antibody

产品货号

YM-A15678

规格

50μL;100μL

种属反应

Human,Monkey

实验应用

WB,IHC,IF,ELISA

分子量

64kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CDC25B around the phosphorylation site of Ser353. AA range:319-368

特异性

Phospho-Cdc25B (S353) Polyclonal Antibody detects endogenous levels of Cdc25B protein only when phosphorylated at S353.

基因名称

CDC25B

蛋白名称

M-phase inducer phosphatase 2

别名

CDC25B;CDC25HU2;M-phase inducer phosphatase 2;Dual specificity phosphatase Cdc25B

基因ID-1

994

SwissProt

P30305

背景

cell division cycle 25B(CDC25B) Homo sapiens CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole .