Cdc25A (phospho Ser178) Polyclonal Antibody

产品详情

产品名称

Cdc25A (phospho Ser178) Polyclonal Antibody

产品货号

YM-A15717

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

59kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser178. AA range:144-193

特异性

Phospho-Cdc25A (S178) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S178.

基因名称

CDC25A

蛋白名称

M-phase inducer phosphatase 1

别名

CDC25A;M-phase inducer phosphatase 1;Dual specificity phosphatase Cdc25A

基因ID-1

993

SwissProt

P30304

背景

cell division cycle 25A(CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位

intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,