Claudin-5 (phospho Tyr217) Polyclonal Antibody

产品详情

产品名称

Claudin-5 (phospho Tyr217) Polyclonal Antibody

产品货号

YM-A16034

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,WB,ELISA

分子量

23kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Claudin 5 around the phosphorylation site of Tyr217. AA range:169-218

特异性

Phospho-Claudin-5 (Y217) Polyclonal Antibody detects endogenous levels of Claudin-5 protein only when phosphorylated at Y217.

基因名称

CLDN5

蛋白名称

Claudin-5

别名

CLDN5;AWAL;TMVCF;Claudin-5;Transmembrane protein deleted in VCFS;TMDVCF

基因ID-1

7122

SwissProt

O00501

背景

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008],

细胞定位

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.