Tuberin (phospho Tyr1571) Polyclonal Antibody

产品详情

产品名称

Tuberin (phospho Tyr1571) Polyclonal Antibody

产品货号

YM-A16061

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

170kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human TSC2 around the phosphorylation site of Tyr1571. AA range:1537-1586

特异性

Phospho-Tuberin (Y1571) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at Y1571.

基因名称

TSC2

蛋白名称

Tuberin

别名

TSC2;TSC4;Tuberin;Tuberous sclerosis 2 protein

基因ID-1

7249

SwissProt

P49815

背景

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.