DDX5 (phospho Tyr593) Polyclonal Antibody

产品详情

产品名称

DDX5 (phospho Tyr593) Polyclonal Antibody

产品货号

YM-A16089

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5 around the phosphorylation site of Tyr593. AA range:565-614

特异性

Phospho-p68 RNA Helicase (Y593) Polyclonal Antibody detects endogenous levels of p68 RNA Helicase protein only when phosphorylated at Y593.

基因名称

DDX5

蛋白名称

Probable ATP-dependent RNA helicase DDX5

别名

DDX5;G17P1;HELR;HLR1;Probable ATP-dependent RNA helicase DDX5;DEAD box protein 5;RNA helicase p68

基因ID-1

1655

SwissProt

P17844

背景

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

细胞定位

Nucleus . Nucleus, nucleolus . Cytoplasm . During the G0 phase, predominantly located in the nucleus. Cytoplasmic levels increase during the G1/S phase. During the M phase, located at the vicinity of the condensed chromosomes. At G1, localizes in the cytoplasm. .