Synapsin I (phospho Ser605) Polyclonal Antibody

产品详情

产品名称

Synapsin I (phospho Ser605) Polyclonal Antibody

产品货号

YM-A16094

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,ELISA

分子量

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

The antiserum was produced against synthesized peptide derived from human Synapsin1 around the phosphorylation site of Ser605. AA range:576-625

特异性

Phospho-Synapsin I (S605) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S605.

基因名称

SYN1

蛋白名称

Synapsin-1

别名

SYN1;Synapsin-1;Brain protein 4.1;Synapsin I

基因ID-1

6853

SwissProt

P17600

背景

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

细胞定位

Cell junction, synapse. Golgi apparatus .