MLK3 (phospho Ser674) Polyclonal Antibody

产品详情

产品名称

MLK3 (phospho Ser674) Polyclonal Antibody

产品货号

YM-A16147

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,IHC

分子量

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;IHC 1:50-300

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)

特异性

Phospho-MLK3 (S674) Polyclonal Antibody detects endogenous levels of MLK3 protein only when phosphorylated at S674.

基因名称

MAP3K11

蛋白名称

Mitogen-activated protein kinase kinase kinase 11

别名

MAP3K11;MLK3;PTK1;SPRK;Mitogen-activated protein kinase kinase kinase 11;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase

基因ID-1

4296

SwissProt

Q16584

背景

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.