Trk B (Phospho Y817) Polyclonal Antibody

产品详情

产品名称

Trk B (Phospho Y817) Polyclonal Antibody

产品货号

YM-A16191

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

IHC,IF,WB

分子量

145kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

IHC 1:50-200;WB 1:500-2000;IF 1:50-200

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized peptide derived from human Trk B (Phospho-Y817)

特异性

This antibody detects endogenous phospho levels of Trk B (Phospho-Y817) Polyclonal Antibody at Human, Mouse, Rat

基因名称

NTRK2 TRKB

蛋白名称

Trk B (Phospho-Y817) Polyclonal Antibody

别名

BDNF/NT-3 growth factors receptor;GP145-TrkB;Trk-B;Neurotrophic tyrosine kinase receptor type 2;TrkB tyrosine kinase;Tropomyosin-related kinase B;

基因ID-1

4915

SwissProt

Q16620

背景

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

细胞定位

Cell membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Early endosome membrane . Cell projection, axon . Cell projection, dendrite . Cytoplasm, perinuclear region . Cell junction, synapse, postsynaptic density . Internalized to endosomes upon ligand-binding. .