CaMK2 (Phospho Thr286) Antibody

产品详情

产品名称

CaMK2 (Phospho Thr286) Antibody

产品货号

YM-A16193

规格

50μL;100μL

种属反应

Human,Mouse,Rat

实验应用

WB,ELISA

分子量

54kD

宿主

Rabbit

同种型

IgG

修饰

Phospho

推荐稀释比

WB 1:500-2000;ELISA(peptide)1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

纯化工艺

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

克降性

Polyclonal

克隆号

免疫原

Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)

特异性

This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)

基因名称

CAMK2D CAMKD

蛋白名称

CaMK2 (Phospho-Thr286)

别名

Calcium/calmodulin-dependent protein kinase type II subunit delta;CaM kinase II subunit delta;CaMK-II subunit delta;

基因ID-1

817

SwissProt

Q9UQM7;Q13557

背景

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

细胞定位

Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .